We are always happy to see Prostate Cancer Research make it into the public forum. And this month we are proud to say our board member Ranjan J. Perera, is leading groundbreaking research in Putative Biomarkers for Prostate Cancer Detection. IPCF is proud to say, last year we awarded a grant to the Sanford-Burnham Institute for Medical Research, which resulted in this landmark research for prostate cancer biomarkers.
Prostate cancer is the leading cause of cancer and the second leading cause of cancer related death in males. While much work has been done in the realm of prostate cancer diagnosis there is still no agreement on a single diagnostic marker to be used for definitive diagnosis. Markers that are frequently used as diagnostic tools of prostate cancer include PSA and PCA3. Both markers however have limitations. PSA may lead to certain confusing situations when some other diseases such as inflammation (prostatitis) or benign prostate hyperplasia can provoke the same degree of PSA changes. PCA3 as a urine marker was recently introduced in wide clinical practice. Although it is proven to exclude prostate cancer, the overall value of this test is limited to predict aggressive nature of the disease. This leaves room for improvement in the detection of prostate cancer.
In this collaborative study done at the Sanford-Burnham Medical Research Institute and Global Robotics Institute six main genes are searched in as a potential diagnostic tools to improve the diagnosis and risk stratification of prostate cancer. These are small molecules of RNA (ribonucleotide acids) that can play a crucial role in cancer development and progression. These molecules can be found in prostate tissue as well as in urine or blood.
The study consisted of 3 parts. The first one compared the level of this molecular gene information between healthy versus cancerous prostate tissue from laboratory-produced prostate cancer cells. The second analysis included a comparative measurement of these molecules from biopsy tissue of patients with and without prostate cancer. The third one performed an analysis of urine samples for these molecules between normal and cancerous patients. What was found was that these RNA structures were found in significantly increased levels in all cancer groups in comparison to the non-cancerous groups.
The initial results of this study demonstrated the promising value of newly discovered gene molecules as additional diagnostic tools that can be detected in tissue, blood and urine. We can combine the use of these markers with additional parameters such as PSA and PCA3 to increase the accuracy of diagnosing prostate cancer. Additional studies may be carried out to further evaluate the utility of these markers.
To download the full article click here, and download from the right hand side of the page.
Posted by endprostatecancer on June 10, 2015
image purchased at istock.com
We all know that Dogs are amazing creatures, not only are they man’s loyal best friend, they often aid us by performing jobs to help better society. Drugs, explosives, and blood, are just a few of the things dogs have been trained to sense. They have also proved successful in tracking other animals, missing persons and suspects to aid police. There is even evidence to suggest those powerful sniffers can aid in early detection of cancer!
Published studies have shown that dogs can detect early stage cancer with 88% specificity, and 99% sensitivity. You may have even seen some cases in the media where a woman’s pet alerted them to breast cancer growing within her. There is no denying a dog’s extraordinary sense of smell. While we have around 5 million olfactory cells in our noses – receptors that detect different odors – dogs have approximately 200 million. It is dogs’ acute ability to trace scents that has made them so attractive to the medical world. More recently, those cuddly canines appeared in the news again for the detection of prostate cancer!
- Italian researchers say they’ve trained two female German shepherd dogs to sniff out prostate cancer and the canines have greater than 90% accuracy.
- The research team from the Humanitas Clinical and Research Center in Milan, Italy collected urine samples from 362 men diagnosed with prostate cancer at various stages of the disease. They also collected urine samples from 418 men and 122 women who were either healthy, had a different kind of cancer or who had a different health condition.
- They then trained Zoe and Liu, three-year-old bomb detection dogs who worked with the Italian armed forces, to detect specific volatile organic compounds in urine associated with prostate cancer.
- After the dogs were retrained, they were tested using batches of six urine samples from the men with prostate cancer, positioned at random among the non-prostate cancer urine samples.
- (bulleted information from http://hometestingblog.testcountry.com/?p=28359)
This is an interesting development and we are excited to follow it and watch it develop. So remember, your dog isn’t just a wonderful companion in your life, he’s a hero that could save it! For more information on dogs detecting cancer, please visit some of the resources below.
Posted by endprostatecancer on April 29, 2015
Here at the International Prostate Cancer Foundation we are lucky to have the support of our many esteemed board members.
They donate their time, expertise and financial support to continuing our efforts to fight prostate cancer and it’s effects.
Recently, board member Wilson Dondo, has contributed his time and efforts to help secure a financial gift from a prostate cancer survivor. Donations like this are important in our continued research and developments of treatments to continue to make an impact in the field of prostate cancer. And having wonderful board members, like Mr. Dondo fighting in our corner, contributes to continued breakthroughs.
Mr. Dondo joined our board in early 2014, he holds a Masters Degree in Marketing as well as a Business Degree. He is a member of the International Prostate Cancer Foundation board and co- founder of VMD Group. He continues to lend his efforts to fundraising for IPCF.
We are proud to have someone as a member of our board who gives back to our community so generously.
If you would like to donate to the International Prostate Cancer Foundation, please contact us at email@example.com or donate directly here.
Posted by endprostatecancer on March 16, 2015
Congratulations to our Founder, Dr. Vipul Patel. He and his team at the Global Robotics Institute completed 8,000 surgeries today! Visit us at @endprostatecancer on twitter and wish him congratulations!
Posted by endprostatecancer on February 3, 2015
Our Founder Dr. Vipul Patel was recently honored with coverage in November’s issue of Life in Keene’s Pointe. Promoting November and Prostate Cancer Awareness Dr. Patel is always happy to lend his time and efforts. Here at The International Prostate Cancer Foundation we are always excited about opportunities to spread awareness and educate men on the importance of screening!
Posted by endprostatecancer on January 5, 2015
It’s that time of year again, time for men everywhere to grow their mustache in support of men’s health! We continue to fulfill our foundation mission to educate by creating awareness and honoring the survivors that give their time to our cause!
This year, we sponsored the #MagicMustache Night held by Orlando Magic and Florida Hospital. On November 1, 2014, survivors and supporters alike joined together to spread the word about prostate cancer. Founder Dr. Vipul Patel and board member Oscar Robertson hosted a pre-game reception, a half time presentation, and tribute to the prostate cancer survivors in attendance.
Social Media and Television helped us spread the word and create a buzz. Fox Sports interviewed Oscar during Pre-Game, and you can see they had a little mustache fun on air! Live tweets and other social media posts were fed live on the center court screen throughout the evening.
With over 15,000 attendees, the night was a great success, educating and honoring the community and survivors! Let’s keep this momentum going throughout the month of November. If you haven’t already grown your mustache , then get started! Create your own social media campaign among your friends and colleagues, after all it’s for a great cause.
We encourage you this month to grow that mustache and Share it to our Facebook page! Don’t forget the hash tag. #magicmustache
Posted by endprostatecancer on November 12, 2014
We are proud sponsors of this year’s Cycle in the City!
IPCF joins Florida Hospital in recognizing the importance of whole person health and the benefits of physical fitness to elevate the wellbeing of our community. With a focus on mind, body and spirit, Corporate Synergies presents Florida Hospital’s Cycle the City | Ride to Wellness, an event to inspire, empower and enable our community to live healthier, more fulfilling lives.
Open to riders of all skill levels, our hope is that this event provides a venue for camaraderie, exercise and inspiration to live happier,
more fulfilling lives.
Posted by endprostatecancer on October 9, 2014
As one of the missions of the International Prostate Cancer Foundation being education, it is no surprise that one of the most outstanding qualities of our founder Dr. Vipul Patel, is his constant commitment to education worldwide. Educating patients on the importance of regular prostate cancer screenings along with the multiple treatment options is a strong focus. Learning as much as possible about the many different treatment options that are available, will enable patients to make better decisions. Treatment options are based on a number of factors and should be made hand in hand with a physician. Options include but are not limited to:
- Prostatectomy – A common treatment for early stage localized cancer in which the prostate gland is removed.
- Radiation Therapy – A treatment in which radioactive exposure is directed at cancer cells and the surrounding tissues.
- External Beam Radiation Therapy – As the most common type of radiation therapy, CT scans and MRIs are used to find the location of the tumor cells.
- Proton Therapy – Unlike the external beam radiation, this form of treatment uses protons for advanced precision on targeted tumors without affecting surrounding tissues.
- Brachytherapy – Tiny radioactive metal pellets are inserted into the prostate. The pellets give off radiation to the immediate surrounding area, killing prostate cancer cells.
- Hormone Therapy – This treatment is designed to prevent testosterone from being released or from acting on the prostate cells, as testosterone is the main fuel source for prostate cancer cell growth.
- Chemotherapy – An advanced prostate cancer treatment option, that involves the use of specific chemicals to stop the cancer cells from dividing, limiting growth and spread of the tumor.
- Emerging Therapies – Everyday new drugs, new regimens and new treatment options are being investigated by researchers all over the world.
Recently Dr. Vipul Patel was interviewed about the benefits of robotic prostatectomy. As one of the leading treatments, the benefits of this procedure by far outweigh the costs.
Allowing the physician great control and comfort, robotic surgeries provide less stress overall, for both the medical staff and the patient. Dr. Patel, his team and surgeons everywhere, have experienced greater control of the overall treatment outcomes with this rapidly growing option in cancer treatments.
For the full interview click HERE.
Posted by endprostatecancer on April 3, 2014
Antioxidants have been shown to play a serious role in preventing free radical damage. While free radicals are found naturally in the body and play a vital role in many normal cellular processes, at a high level they can be dangerous to the body and cause damage to major cells, including DNA cells. Damage to DNA cells may be connected to the development of cancer and other health conditions.
Antioxidants can be found in high quantities in bright colored fruits, dried beans, and nuts. Remembering to “eat the rainbow” at every meal, will help ensure that your diet is chalk full of cancer fighting antioxidants.
Below is a perfect example of a dinner with tons of cancer fighting ingredients from iVillage.com.
Salmon with Blueberry Mango Salsa
Image from iVillage.com
- 4 – 4 ounce Salmon Fillets
- 1/2 teaspoon Extra-Virgin Olive Oil
- 1/4 teaspoon Sea Salt
- Pinch fresh ground Black Pepper
- 1/3 cup diced Mango
- 1/3 cup Blueberries
- 1 tablespoon fresh Lime Juice
- 2 tablespoons minced Red Onion
- 2 tablespoons minced Red Bell Pepper
- 1 tablespoon minced fresh Cilantro
- 1/2 teaspoon minced Jalapeños
- 2 teaspoons evaporated Cane Juice
Very Easy Directions:
1. Mix up the blueberry mango salsa ingredients in a medium bowl. Lightly crush with a fork to release juices and set a side.
2. Heat olive oil in a large sauté pan over medium-high heat. Season salmon with salt and pepper and sear for 3 to 5 minutes on each side (or until cooked through).
3. Serve each salmon fillet with 1/4 cup of salsa.
This yummy dinner idea can be recreated with a variety of fruits and berries. Use whats in season or what you have on hand. Just make sure its colorful!
Content Citation: Pharmacogn Rev. 2010 Jul-Dec; 4(8): 118–126. Find out more about free radicals and antioxidants and how they impact the human body, HERE.
Posted by endprostatecancer on March 28, 2014
Dr. Kenneth Palmer, International Prostate Cancer Foundation Secretary & Director of Global Robotics Institute in Latin America, was on CNN Español. Dedicated to educating prostate cancer patients and their families, Dr. Palmer discusses many prostate cancer related topics. The full interview can be viewed below.
Posted by endprostatecancer on March 18, 2014